VITAMIN D ANALOG Russian patent published in 1995 - IPC

FIELD: a preparation of wide spectrum of activity. SUBSTANCE: the product an analog of vitamin D of the formula I in which is an integer of 1 to 6 R₁ and R₂ are the same or different H, CH, CH, i-CH or together with the carbon atom marked by an asterisk and with radicals R₁,R₂ and X form a cyclohexane ring; X is H or OH. Preferable compounds 1(S), 3(R)-dihydroxy-20(R)-4'- hydroxy-4'-ethyl-1'-hexyloxy)-9,10-sec.pregna-5(Z), 7(E), d(19)-triene, 1(S), 3(R)-dihydroxy-20(R)'-(6'-hydroxy-1'- hexyloxy, 9,10-sec. pregna-5(Z), 7(E), 10(19) triene, 1(S), 3(R) dihydroxy-20(R)-5'-hydroxy-5'-ethyl-1'- heptyloxy), 9,10-sec.pregna-5(Z), 7(E), 10(19)-triene, 1(S), 3(R)-dihydroxy-20(R)-5'-methyl-5'-ethyl-1'- hexyloxy, 9,10-sec.pregna-5(Z), 7(E), 10(19)-triene. The structure of the formula I. EFFECT: improved properties of the title product. 2 cl, 3 tbl