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(19)

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2 037 495

(13)

(51)

IPC

(21) (22)

Application

4895183/04, 1991-04-18

(22)

Actual filing date

1991-04-18

(45)

Published

1995-06-19

(72)

Inventor

Ljudo Ehdmond Zhozefin Kennis[Be]Jan Vandenberk[Be]Al'Bertus Khendrikus Marija Terezija Van Khehrtum[Be]

(73)

Holder

Zhansen Farmasetika N.V.

2,9-DISUBSTITUTED 4H-PYRIDO-(1,2-A)-PYRIMIDINE-4-ONES AND ANTIPSYCHOTIC COMPOSITION Russian patent published in 1995 - IPC

Abstract RU 2037495 C1

FIELD: organic chemistry. SUBSTANCE: product: 2,9-disubstituted 4H-pyrido-[1,2-a]-pyrimidine-4-ones of the formula (I) or their pharmaceutically acceptable salts, and antipsychotic compositions containing compounds of the formula (I) at quantity 0.25-5 mg per a dose and acceptable carrier. Compounds of the formula (I) were synthesized by N-alkylation of 3-piperidinyl-1,2-benzoxazole or cyclization of corresponding oxime or its derivative. Synthesized compounds were used in medicine. EFFECT: improved method of synthesis. 5 cl, 4 tbl

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RU 2 037 495 C1

Authors

Ljudo Ehdmond Zhozefin Kennis[Be]

Jan Vandenberk[Be]

Al'Bertus Khendrikus Marija Terezija Van Khehrtum[Be]

Dates

1995-06-19—Published

1991-04-18—Filed