FIELD: organic chemistry. SUBSTANCE: product: 2,9-disubstituted 4H-pyrido-[1,2-a]-pyrimidine-4-ones of the formula (I) 
or their pharmaceutically acceptable salts, and antipsychotic compositions containing compounds of the formula (I) at quantity 0.25-5 mg per a dose and acceptable carrier. Compounds of the formula (I) were synthesized by N-alkylation of 3-piperidinyl-1,2-benzoxazole or cyclization of corresponding oxime or its derivative. Synthesized compounds were used in medicine. EFFECT: improved method of synthesis. 5 cl, 4 tbl
| Title |
Year |
Author |
Number |
| RISPERIDONE PAMOATE, METHOD OF ITS SYNTHESIS, ANTIPSYCHOTIC COMPOSITION ON ITS BASE AND METHOD OF ITS PREPARING |
1994 |
- Zhan Lui Mesens
- Jozef Pehters
|
RU2131428C1 |
| ESTER DERIVATIVES OF 9-HYDROXY-PYRIDO[1,2-A]PYRIMIDINE-4-ONE, A METHOD OF THEIR SYNTHESIS, A COMPOSITION SHOWING ANTIPSYCHOTIC ACTIVITY AND A METHOD OF ITS PREPARING |
1994 |
- Jan Vandenberk
- Ljudo Ehdmon Zhozefin Kenni
|
RU2126406C1 |
| METHOD FOR PREPARATION OF 3-PIPERAZINYLBENZAZOL DERIVATIVES OR THEIRS PHARMACEUTICALLY ACCEPTABLE ADDITIVE SALTS |
0 |
- Lyudo Edmond Zhozefin Kennis
- Yan Vandenbek
- Zhozefus Karolus Mertens
|
SU1687030A3 |
| METHOD OF PRODUCING DERIVATIVES OF 1,2-BENZISOXAZOLYL-3, OR 1,2-BENZISOTHIAZOLYL-3 OR STEREOSIOMERS THEREOF OR ACID-ADDITIVE SALTS THEREOF |
0 |
- Lyudo Edmon Zhozefin Kennis
- Yan Vandenberk
|
SU1468419A3 |
| RISPERIDONE-CONTAINING MICROCAPSULES, PHARMACEUTICAL COMPOSITION AND METHODS OF THEIR MAKING |
1994 |
- Mesens Zhan-Lui
- Riki Majkl E.
- Atkins Tomas Dzh.
|
RU2178695C2 |
| DERIVATIVES OF PYRAMIDINE-4-ONE OF THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND SEROTONIN-ANTAGONISTIC, DOPAMINE-ANTAGONISTIC AND ANTIGISTAMINE COMPOSITION ON THEIR BASES |
1990 |
- Lido Ehdmon Zhozefin Kennis[Be]
- Jan Vandenberk[Be]
- Jozef Martin Buj[Be]
|
RU2028297C1 |
| METHOD FOR PRODUCING DERIVATIVES OF (1-PIPERIDINYL-ALKYL) PYRIMIDINONE |
0 |
- Ludo Edmond Zhozefine Kennis
- Yan Vandenberk
- Jozef Karolus Mertens
|
SU1313349A3 |
| METHOD OF OBTAINING DERIVATIVES OF BICYCLIC PYRAMIDINE-5-ON OR THEIR SALTS WITH PHARMACEUTICALLY ACCEPTABLE ACIDS OR THEIR CIS- OR TRANS-ISOMERS |
0 |
- Lyudo Edmon Zhozefin Kennis
- Jozefus Karolus Mertens
|
SU1138032A3 |
| PROCESS FOR PREPARING DERIVATIVES OF 4H-PYRIDO(1,2-A)PYRIMIDIN-4-ONE OR THEIR PHARMACUETICALLY ACCEPTABLE ACID ADDITION SALTS |
0 |
- Lyudo Edmon Zhozefin Kennis
- Zhozefin Karolyus Mertens
|
SU1093251A3 |
| METHOD OF SYNTHESIS OF DERIVATIVES OF N-(3-HYDROXY-4-PIPERIDINYL)-(DIHYDROBENZOFURAN, DIHYDRO-2H-BENZOPYRAN OR DIHYDROBENZODIOXINE)-CARBOXAMIDE, OR THEIR SALTS, OR THEIR STEREOCHEMICALLY ISOMERIC FORM |
1990 |
- Zhorzh Anri Pol' Van Del'[Be]
- Frans Marija Al'Fons Van Den Kejbus[Be]
|
RU2037492C1 |
