FIELD: biochemistry and medicine. SUBSTANCE: derivatives of pyrimidine-4-one of formula 1 at definite values of radicals, or their PHARMACEUTICALLY acceptable salts possessing serotonin-antagonistic, dopamine-antagonistic and antihistamine activities and composition containing said derivatives of pyrimidine-4-one and inert carrier. Reagent 1: compound of formula 11. Reagent 2: compound of formula lll, where W=N is reaction split-off group at respective said values of radicals. Process is conducted in inert solvent in presence of base. Compound structures of formulas l, ll and lll are given in invention description. EFFECT: higher efficiency.
| Title |
Year |
Author |
Number |
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1990 |
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1993 |
- Zhorzh Anri Pol' Van Del'[Be]
- Frans Marija Al'Fons Van Den Kejbus[Be]
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| HYDROXYALKYLFURAN DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS |
1990 |
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1991 |
- Frans Ehduard Zhanssen[Be]
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1990 |
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1993 |
- Zhorzh-Anri Pol' Van Dael'
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- Uilli Dzhouns Karolus Van Laerovan
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1989 |
- Zhan P'Er Frans Van Vov[Be]
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1992 |
- Mikhail Zhozef Kjukla[Us]
- Anri Zhozef Breslin[Us]
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