ESTER DERIVATIVES OF 9-HYDROXY-PYRIDO[1,2-A]PYRIMIDINE-4-ONE, A METHOD OF THEIR SYNTHESIS, A COMPOSITION SHOWING ANTIPSYCHOTIC ACTIVITY AND A METHOD OF ITS PREPARING Russian patent published in 1999 - IPC

Abstract RU 2126406 C1

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention proposes ester derivatives of 9-hydroxy-pyrido[1,2-a] pyrimidine-4-one of the formula (I) where Alk is C1-4-alkanediyl; D - heterocycle of the formula (a) or (b) ; R1 is C2-6-alkenyl, C2-6-alkynyl, C1-19-alkyl possibly substituted with C1-6-alkoxy- or cyano-group; each of R2 - hydrogen or C1-4-alkyl, or its isomers, or its pharmaceutically acceptable acid salt that show antipsychotic activity. EFFECT: improved method of synthesis, enhanced effectiveness.

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RU 2 126 406 C1

Authors

Jan Vandenberk

Ljudo Ehdmon Zhozefin Kenni

Dates

1999-02-20Published

1994-11-16Filed