METHOD OF SYNTHESIS OF SUBSTITUTED PURINE ARABINOSIDES OR THEIR PHARMACEUTICALLY ACCEPTABLE DERIVATIVES Russian patent published in 1995 - IPC

FIELD: organic chemistry. SUBSTANCE: product: substituted derivatives of purine arabinosides of the formula (I) where R₁ halogen, methoxy, ethoxy, propoxy, amino-group which is monosubstituted with methyl or C-C -cycloalkyl, or disubstituted with C-C-alkyl, or R₁ nitrogen-containing heterocycle; R₂ hydrogen, halogen or amino-group at condition that when R₂ hydrogen then R₁ does not methoxy, methylamino, dimethylamino, piperidino or pyrrolidino-group, and when R₂ amino-group then R₁ does not methylamino-group, and/or its pharmaceutically acceptable derivatives, except for 2,3,5-triacetate and 2,3,5-tribenzyl-derivatives of the formula (I) where R₁ chlorine or fluorine and R₂ - chlorine, fluorine, hydrogen or amino-group. Reagent 1: compound of the formula (II) . Reagent 2: compound of the formula (III) . Synthesized compounds were used in medicine. EFFECT: improved method of synthesis.