FIELD: organic chemistry, purine nucleosides. SUBSTANCE: invention relatestomono-,di-ortricomplexestersof2-amino-6-(C1-C5-alkoxy)-9-(β-D-arabinofuranosyl)-9H-purine of the general formula (I): 
where arabinofuranosyl residue is substituted at 2'-, 3'- or 5'-positions and esters are formed by carboxylic acids where noncarbonyl moiety is taken from n-propyl, tert. -butyl, n-butyl, methoxymethyl, benzyl, phenoxymethyl, phenyl, methanesulfonyl and succinyl. Compounds of the formula (I) 
aresynthesizedbyesterificationof2-amino-6-methoxy-9-β-D-arabinofuranosyl-9H-purine in the presence of enzyme being hydroxyl group is protected. Invention describes pharmaceutical forms containing compounds of the formula (I) 
taken at effective amount showing antitumor effect alco. EFFECT: improved method of synthesis, enhanced antitumor activity of compounds. 13 cl
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| ENANTIOMERIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF | 1992 |
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| METHOD OF PRODUCING GUANINE DERIVATIVES OR THEIR ACID=ADDITIVE SALTS SUITABLE FOR PHARMACY | 0 |
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