PROCESS FOR PREPARING PEPTIDE Russian patent published in 1995 - IPC

FIELD: processes for preparing peptides (new biologically active compounds) which can be used for medical purposes. SUBSTANCE: agents based on the resulting peptide are capable of producing an antialcoholic effect individually or in combination with other pharmacological agents of peptide origin. Synthesis of a compound of the formula: A-TYR-PRO-SER-NH-B, wherein A is H-TYR or X-TYR-Y-PHE-Z, X is H or an optically active basic aminoacid, Y is D-aminoacid, Z is an optically active aminoacid, B is H or an alkyl group, is carried out in a solution, the BOC-SER (BZL)-NH-B fragment is first condensed in the presence of N-methylmorpholine, and liquid chromatography is carried out on Diasorb-130 in an acetonitrile solution. EFFECT: more efficient preparation process. 2 dwg, 1 tbl