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2 060 729

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IPC

(21) (22)

Application

93012790/14, 1993-03-09

(22)

Actual filing date

1993-03-09

(45)

Published

1996-05-27

(72)

Inventor

Podkujko V.N.Afanas'Ev S.S.Denisov L.A.Pchelintsev S.Ju.Vorob'Ev A.A.Kalinin Ju.T.Marchenko V.I.Shcherbakov G.Ja.

(73)

Holder

Kalinin Jurij Tikhonovich

METHOD OF PREPARING PERORAL MEDICINAL FORM OF CYTOKINE (ITS VARIANTS) Russian patent published in 1996 - IPC

Abstract RU 2060729 C1

FIELD: medicine, pharmacy. SUBSTANCE: cytokine is mixed with filler which is obtained by mixing lactose, sucrose and calcium stearate. Filler is granulated in the fluidized layer with cytokine solution and sprayed the intestine-soluble coating containing oleic acid, ammonia, shellac and water. Invention has 2 variants. Method can be used for preparing peroral cytokine forms, for example, alpha- or gamma-interferon, "ФНО"-alpha, etc. EFFECT: improved method of cytokine form preparing. 3 cl

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RU 2 060 729 C1

Authors

Podkujko V.N.

Afanas'Ev S.S.

Denisov L.A.

Pchelintsev S.Ju.

Vorob'Ev A.A.

Kalinin Ju.T.

Marchenko V.I.

Shcherbakov G.Ja.

Dates

1996-05-27—Published

1993-03-09—Filed