FIELD: organic chemistry. SUBSTANCE: product: corticoid-17-alkylcarbonates of the formula 
where R1 - O-acyl of the formula -O-CO-(CH2)n-R3; n = 0, 1, 2; R3 - C1-C3-alkyl; R2 - branched C3-C6-alkyl. Product is obtained by acid hydrolysis of the corresponding 17,21-orthoether using weak acid followed by esterification of obtained 21-hydroxy-derivative of the formula 
. Synthesized compounds were used as antiinflammatory preparations. ???EFFECT: improved method of synthesis. 2 cl, 9 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| CARBOXYLIC ACID 17-DEOXYCORTICOID-21-ESTER, METHODS OF ITS SYNTHESIS, DRUG | 1995 |
|
RU2161624C2 |
| SUBSTITUTED AZOLES AND A METHOD OF THEIR SYNTHESIS | 1991 |
|
RU2047604C1 |
| METHOD FOR PRODUCTION OF POLYOLEFINS | 1992 |
|
RU2078771C1 |
| METHOD OF PREPARING CORTICOID-21-SULFOPROPINATES OR THEIR SALTS | 0 |
|
SU818489A3 |
| IMIDAZO-ANNELATED ISO- AND HETEROCYCLES AND METHOD FOR THEIR PRODUCTION | 1992 |
|
RU2076105C1 |
| METALLOCENES WITH ARYL-SUBSTITUTED INDENYL DERIVATIVES, METHOD OF SYNTHESIS OF OLEFIN POLYMERS AND CATALYST FOR OLEFINS POLYMERIZATION | 1993 |
|
RU2118961C1 |
| PROCESS FOR PRODUCING CORTICOIDES | 0 |
|
SU927123A3 |
| SUBSTITUTED DERIVATIVES OF CYCLOHEXANE | 1993 |
|
RU2126378C1 |
| PROCESS FOR PREPARING 17 ALPHA-ALKOXYMETHOXY CORTICOIDS | 0 |
|
SU1103797A3 |
| BASE-SUBSTITUTED BENZOYLGUANIDINES, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION, METHOD OF ITS PREPARING AND METHOD OF INHIBITION OF CELLULAR Na/H-ANTIPORTER | 1996 |
|
RU2161604C2 |
