METHOD OF SYNTHESIS OF PEPTIDES, PEPTIDES, IMMUNOMODULATING COMPOSITION AND A METHOD OF REGULATION OF INSUFFICIENT OR EXCESSIVE FUNCTION OF T-CELLS IN PATIENT Russian patent published in 1996 - IPC

FIELD: medicine. SUBSTANCE: peptides of the formula I: R-Arg-X-Y-Z-R₁ where R - hydrogen, acetyl, formyl; X - proline (Pro); Y - L-Ala, L-Asp, L-Val; Z - L-Val, L-Ala; R₁ - H, OH, NH₂, NH(CH₃), NHCH(CH₃)₂, methods of their synthesis by solid-phase procedure using cellulose, polyvinyl alcohol, polymethylmethacrylate, polystyrene and polystyrenedivinylbenzene as a backing for polymer or copolymer, or in the solution by step-stage or block amino acid or peptide fragment connection. Composition contains at least one peptide of the formula I as an active substance at the effective amount. EFFECT: improved method of synthesis. 10 cl, 8 dwg, 5 tbl