PEPTIDE WITH IMMUNO-SIMULATING ACTIVITY AND PREPARATION BASED ON SUCH PEPTIDE Russian patent published in 1999 - IPC

Abstract RU 2142958 C1

FIELD: peptide synthesis. SUBSTANCE: invention provides new peptide with general formula I: (I) wherein R is hydrogen, lower alkyl, or lower acyl; X heteroaromatic amino acid residue; and n=1 or 2; on condition that, when residue RNHCH(COOH)(CH2)nCO- is glutamic acid residue (n= 2), then X has stereo configuration different from that at alpha-carbon atom of glutamic acid having immuno-simulating activity. Preparation having such activity and containing peptide I (0.001 to 0.01 %) and special additives (the balance) is also provided. EFFECT: enlarged choice of immuno-simulating peptides. 2 cl, 11 tbl, 15 ex

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RU 2 142 958 C1

Authors

Kolobov A.A.

Simbirtsev A.S.

Dates

1999-12-20Published

1997-12-25Filed