METHOD OF STIMULATION OF HYBRIDOMAS ASCITIC FORM FORMATION AND MONOCLONAL ANTIBODIES YIELD INCREASE Russian patent published in 1996 - IPC

Abstract RU 2063437 C1

FIELD: biotechnology. SUBSTANCE: method involves the use of adjuvant consisting of cyanophyceae algae lipopolysaccharide, Vaseline, cholesterol, Tween and Spun to stimulate hybrid cell ascitic tumors producing monoclonal antibodies. Adjuvant is administrated 7-8 days before inoculation of hybrid cells at amount 0.5 ml per a mouse. EFFECT: improved method of stimulation and antibody yield increase. 2 tbl

Similar patents RU2063437C1

Title	Year	Author	Number
STRAIN OF CULTURED HYBRID CELLS OF ANIMAL MUS MUSCULUS - A PRODUCER OF MONOCLONAL ANTIBODY RAISED TO THERMOSTABLE SURFACE ANTIGEN OF MELIODOSIS PATHOGEN	1997	Prokhvatilova E.V. Khrapova N.P. Tikhonov N.G.	RU2116344C1
ANIMAL MUS MUSCULUS FRANCISELLA TULARENSIS 1D6 HYBRID CULTURED CELLS STRAIN - PRODUCER OF TULAREMIA BACTERIA LIPOPOLYSACCHARIDE MONOCLONAL ANTIBODIES	2016	Terekhova Irina Viktorovna Syrova Nataliya Alekseevna Tereshkina Nataliya Evgenevna Mikheeva Elena Aleksandrovna Devdariani Zurab Levanovich	RU2621379C1
STRAIN OF HYBRID CULTURED MAMMALIAN CELLS MUS MUSCULUS L - A PRODUCER OF MONOCLONAL ANTIBODIES SHOWING SPECIFICITY TO BRUCELLA PROTEIN PREPARATION OF MOLECULAR MASS 18 AND 38 KDA	1996	Mikhajlov L.M. Titenko A.M. Zakhlebnaja O.D. Laukner I.V.	RU2113475C1
STRAIN OF CULTURED HYBRID CELLS OF ANIMAL MUS MUSCULUS - PRODUCER OF MONOCLONAL ANTIBODIES TO THERMOSTABLE ANTIGEN WHICH IS COMMON FOR GLANDERS AND MELIODOSIS PATHOGENS	1997	Prokhvatilova E.V. Khrapova N.P. Tikhonov N.G. Kulakov M.Ja.	RU2117043C1
STRAIN OF CULTURED HYBRID CELLS OF ANIMAL MUS MUSCULUS - PRODUCER OF MONOCLONAL ANTIBODIES TO THERMOSTABLE COMPONENT OF CAPSULE-LIKE SUBSTANCE OF MELIODOSIS PATHOGEN	1997	Prokhvatilova E.V. Khrapova N.P. Tikhonov N.G.	RU2117042C1
STRAIN OF HYBRID CULTURED CELLS OF ANIMAL MUS MUSCULUS L - A PRODUCER OF MONOCLONAL ANTIBODIES RAISED TO PIG VESICULAR DISEASE VIRUS, STRAIN T-75	1997	Globenko L.A. Fomenko V.Ju. Zhbanova T.V. Shazhko Zh.A. Drygin V.V. Dudnikov S.A.	RU2117700C1
STRAIN OF HYBRID CULTURED CELLS MUS MUSCULUS - A PRODUCER OF MONOCLONAL ANTI- BODIES USED FOR VIRAL HEMORRHAGIC RABBIT DISEASE DIAGNOSIS	1992	Chernykh A.A. Malogolovkin S.A. Vlasov N.A.	RU2007452C1
STRAIN OF HYBRID ANIMAL CELLS Mus museums L - PRODUCER OF MONOCLONAL ANTIBODIES FOR EXPOSING NUCLEOPROTEIN OF EBOLA VIRUS, ZAIRE SUBTYPE (Mainga STRAIN) (VERSIONS), MONOCLONAL ANTIBODY PRODUCED BY SAID STRAIN (VERSIONS) AND SET FOR "SANDWICH" FORMAT IMMUNOENZYMOMETRIC TEST SYSTEM FOR EXPOSING NUCLEOPROTEIN OF EBOLA VIRUS, ZAIRE SUBTYPE (Mainga STRAIN)	2008	Kazachinskaja Elena Ivanovna Pereboev Aleksandr Vladimirovich Ivanova Alla Vladimirovna Kachko Alla Vasil'Evna Subbotina Ekaterina Leonidovna Chepurnov Aleksandr Alekseevich Razumov Ivan Alekseevich Loktev Valerij Borisovich	RU2395576C1
STRAIN OF HYBRID CULTURED MAMMALIAN CELLS MUS MUSCULUS - A PRODUCER OF MONOCLONAL ANTIBODY TO HERPES SIMPLEX VIRUS TYPE I	1991	Malakhova Irina Vladimirovna[By] Kolomiets Anatolij Gavrilovich[By] Kolomiets Natal'Ja Dmitrievna[By] Luchko Vitalina Pavlovna[By] Gasich Elena Leonidovna[By] Kunitskaja Ljudmila Jakovlevna[By] Rytik Petr Grigor'Evich[By]	RU2031117C1
MUS MUSCULUS'S HYBRID CULTURE CELL STRAIN α PRODUCING MONOCLONAL ANTIBODIES SPECIFIC TO HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR (GCSF)	2013	Davydov Mikhail Ivanovich Baryshnikov Anatolij Jur'Evich Baryshnikov Kirill Anatol'Evich Golubtsova Natal'Ja Valer'Evna Manina Irina Vladimirovna Molodyk Al'Vina Al'Fredovna Ivanov Pavel Konstantinovich	RU2542381C2

RU 2 063 437 C1

Authors

Kryzhanov M.A.

Polosukhina E.R.

Polosukhina Ju.R.

Dates

1996-07-10—Published

1992-01-22—Filed