FIELD: medicine as drugs. SUBSTANCE: product; 1-(3-chloro-phenyl)-4-methyl- 7,8-dimethoxy--2,3-benzodiazepine. Yield: about 80%, mp 168-169c. Reagent 1: 2-acetonyl-3-chloro-4,5- dimethoxybenzophenone. Reagent 2: hydrazine hydrate. Reaction conditions: ratio of reagents is 1: (3-7) in lower aliphatic alcohol at 28-68 C in oxygen-free medium, optionally in the presence of water. EFFECT: improved properties of the title compound. 4 cl, 1 tbl
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Authors
Dates
1996-08-27—Published
1992-04-30—Filed