PROCESS FOR PREPARING 1-(3-CHLOROPHENYL)-4-METHYL-7,8- DIMETHOXY-5H-2,3-BENXODIAZEPINE Russian patent published in 1996 - IPC

Abstract RU 2065852 C1

FIELD: medicine as drugs. SUBSTANCE: product; 1-(3-chloro-phenyl)-4-methyl- 7,8-dimethoxy--2,3-benzodiazepine. Yield: about 80%, mp 168-169c. Reagent 1: 2-acetonyl-3-chloro-4,5- dimethoxybenzophenone. Reagent 2: hydrazine hydrate. Reaction conditions: ratio of reagents is 1: (3-7) in lower aliphatic alcohol at 28-68 C in oxygen-free medium, optionally in the presence of water. EFFECT: improved properties of the title compound. 4 cl, 1 tbl

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Authors

Derd' Shomodi[Hu]

Peter Botka[Hu]

Tamash Khamori[Hu]

Jene Kereshi[Hu]

Chilla Kishsh[Hu]

Tibor Balog[Hu]

Marija Bidlo[Hu]

Djula Khorvat[Hu]

Antal Shimaj[Hu]

Rozha Denge[Hu]

Imre Moravchik[Hu]

Ehrne Orban[Hu]

Ehmilija Ushkert[Hu]

Dates

1996-08-27Published

1992-04-30Filed