FIELD: chemistry of heterocyclic compounds. SUBSTANCE: product: derivatives of triazolylhydrazide of the general formula (I) 
where Q hydrogen, 6-member heterocyclic group containing either one nitrogen and one oxygen or one or two nitrogen and non- or substituted with C1-C4-alkyl group, or group SR1 or NR2R3; R1 - C1-C4-alkyl; R2 and R3 are similar and mean hydrogen, C1-C6-alkyl or linear C2-C6-alkenyl; R7 hydrogen, phenyl-C1-C4-alkyl substituted if necessary with monohalide or amino-group, possibly with mono- or disubstituted C1-C4-alkyl; R8 and Z are different and mean hydrogen or a group of the formula (II) -C(X)-N(R4-NR5R6 where X oxygen or sulfur. Reagent 1: triazolyl ester of the formula (III) 
where R10 and Y are different and mean oxygen or a group -C(X)-XR9. Reagent 2: hydrazine HNR4-NR5R6. Synthesis is carried out by interaction of reagents 1 and 2 under corresponding conditions. Synthesized compounds show sedative, cardiovascular, antiviral and antiulcer effects. EFFECT: improved method of synthesis.
| Title | Year | Author | Number |
|---|---|---|---|
| DERIVATIVES OF 1,2,4-TRIAZOLYLTHIOAMIDES | 1990 |
|
RU2045521C1 |
| DERIVATIVES OF 5-(AMINO-SUBSTITUTED)-1,2,4-TRIAZOLO-[1,5-A]-PYRIMIDINE, THEIR PHARMACEUTICALLY ACCEPTABLE ACID-ADDITIVE SALTS, PHARMACEUTICAL COMPOSITION SHOWING CARDIOTONIC AND CORONARY-DILATING ACTION AND A METHOD OF CARDIOTONIC AND/OR CORONARY-DILATING EFFECT ON HEART | 1992 |
|
RU2097382C1 |
| PROCESS FOR PRODUCTION OF DERIVATIVES OF TRIASOLOPYRIMIDINE OR MIXTURE THEREOF OR THEIR PHARMACEUTICALLY-ACCEPTABLE SALTS WITH METALS | 0 |
|
SU1776261A3 |
| DERIVATIVES OF 2-(1,2,4-TRIAZOLE-1-YL)-1,3,4-THIADIAZOLE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND INTERMEDIATE COMPOUND | 1998 |
|
RU2180903C2 |
| 3-(2-SUBSTITUTED PHENYL)-2-(SUBSTITUTED IMNO) THIAZOLIDINES OR PHARMACEUTICALLY ACCEPTABLE SALTS AND PHARMACEUTICAL COMPOSITION HAVING ANTIANGINAL AND/OR ANTINEUROLOGICAL EFFECT | 1992 |
|
RU2065855C1 |
| DIHYDROPYRIMIDOTHIAZINE DERIVATIVES OR THEIR THERAPEUTICALLY ACCEPTABLE SALTS OF ACID BINDING SHOWING ANTIANGINAL AND ANTIINFLAMMATORY ACTIVITY | 1990 |
|
RU2022965C1 |
| PROCESS FOR PREPARING 1-(3-CHLOROPHENYL)-4-METHYL-7,8- DIMETHOXY-5H-2,3-BENXODIAZEPINE | 1992 |
|
RU2065852C1 |
| THIOACID AMIDE DERIVATIVES AND FOOD COMPOSITION FOR THE USE IN CATTLE BREEDING | 1991 |
|
RU2060995C1 |
| METHOD OF OBTAINING DERIVATIVES OF AMINOALKANOYLDIBENZO(D,Q) (1,3,6)DIAOXASOCIN OR THEIR PHARMACEUTICALLY ACCEPTABLE ADDITIVE SALTS WITH ACIDS | 0 |
|
SU1575938A3 |
| METHOD OF PRODUCING DERIVATIVES OF DIHYDROARYLOXYALKYLAMINO-1,2,4-TRIAZOLE OR THEIR PHARMACEUTICALLY ACCEPTABLE ACID-ADDITION SALTS | 0 |
|
SU1480767A3 |
