FIELD: medicine as antioxidative and antiinflammatory agent. SUBSTANCE: product: glycyrhetic acid derivative of formula 1 wherein R is H or unsubstituted or substituted C-C alkyl or pharmacologically acceptable salt thereof. The product is produced by reacting halogenphosphorylating agent with glycyrhetic acid or alkyl ester thereof followed by reaction of the resulting product with ascorbic acid having protected 5- and 6-hydroxy groups which are then deprotected by hydrolysis. Structure of the compound of formula I: . EFFECT: improved properties of glycyrhetic acid derivatives. 9 cl, 3 dwg, 2 tbl
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Authors
Dates
1996-08-27—Published
1992-03-12—Filed