GLUTATHIONE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND A METHOD OF THEIR SYNTHESIS Russian patent published in 1995 - IPC

Abstract RU 2041201 C1

FIELD: peptide chemistry. SUBSTANCE: product: derivatives of glutathione of the formula (I) where n 0 or 1; R1 H, lower alkyl; R2 and R3 are similar or different OH, lower alkoxy, NH2, imino-group at condition that R1 lower alkyl when n 0, and R3 and R3 are similar or different OH or lower alkoxy-group. Reaction conditions: reagent 1: γ-glutamylcysteinylglycine or its ester. Reagent 2: maleicor itaconic acid or their derivatives. EFFECT: improved method of synthesis. 4 cl, 3 dwg, 4 tbl

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RU 2 041 201 C1

Authors

Sindzi Okhmori[Jp]

Kazumi Ogata[Jp]

Takakhiro Sakau[Jp]

Dates

1995-08-09Published

1991-10-16Filed