ARALKYLSUBSTITUTED IMIDAZOLES SHOWING ANTIHYPERTENSIVE ACTION, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION SHOWING INHIBITING ACTIVITY WITH RESPECT TO ANGIOTENSIN II Russian patent published in 1996 - IPC

FIELD: organic chemistry. SUBSTANCE: products: aralkylsubstituted imidazoles of the formula (I) where R¹-C₂-C₆-alkyl; R² - 1- or 2-naphthyl, 3-, 4- or 5-acenaphthyl, 1-, 2-, 3-, 4- or 9-phenanthrenyl, 2-, 3-, 4-, 5-, 6- or 7-benzofuryl or 2-, 3-, 4-, 5-, 6- or 7-benzothienyl, C₂-C₁₀-alkenyl. Reagent 1: compound of the formula (II) where R¹ and R² as indicated above. Reagent 2: compound of the formula (III) where X¹ - halogen. Reaction conditions: in organic solvent medium, in the presence of the base. Synthesized compounds were used in medicine as antihypertensive agents. ???EFFECT: improved method of synthesis. 4 cl, 8 tbl