FIELD: organic chemistry. SUBSTANCE: product: the substituted 1,2,3-triazole compounds of the general formula (I): where: R1 - C2-6-alkyl; R2 - carboxy- or tetrazolyl-radical. Reagent 1: azide of the formula (II) . Reagent 2: alkane of the formula (III) R′H. Reaction condition: at reaction mixture boiling. Synthesized compounds were used in medicine as antihypertensive agents and for treatment of cardiac failure in mammalian. EFFECT: improved method of synthesis. 3 tbl
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Authors
Dates
1997-03-27—Published
1992-10-12—Filed