ALKYLENEDIAMINE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS Russian patent published in 1996 - IPC

FIELD: chemistry of heterocyclic compounds. SUBSTANCE: product: alkylenediamine derivatives of the formula (I) where one of radical D and E is -CH₂- or -CO- and other is -(CH₂)_m-R¹ and R¹ is hydrogen, lower alkyl, phenyl nonobligatory substituted with halogen atom, lower alkyl or lower alkoxy-group, naphthyl, thienyl or 3-indolyl; R² - phenyl nonobligatory substituted with halogen atom or lower alkyl, thienyl or furyl; R³ and R⁴, each of radical is lower alkyl and radicals R³ and R⁴ were bound and together with nitrogen atom to which they were bound form morpholine, thiomorpholine, homomorpholine, pyrrolidine, piperidine which is nonobligatory substituted with hydroxyl or lower alkoxy-groups, or 4-acetylpiperazine; X and Y - independently each of other, every of radicals is oxygen or sulfur atom; m = 0-4; n = 0-4; r = 0 or 1; each of symbol p and q, independently each of other, means the whole number 0-5 at condition that p + q = 1-5; or their pharmaceutically acceptable salts. Synthesized compounds show capability to inhibit bladder contraction and can be used in medicine for disuria treatment. EFFECT: improved method of synthesis. 2 dwg, 6 tbl