ACTIVATING AGENT FOR RECEPTOR ACTIVATED BY PEROXISOME GROWTH-STIMULATING AGENTS Russian patent published in 2013 - IPC C07D333/56 C07D333/58 C07D209/12 C07D307/80 C07D413/06 A61K31/381 A61K31/343 A61K31/404 A61K31/423 A61P3/06 A61P3/10 

FIELD: chemistry.

SUBSTANCE: invention relates to a compound of formula (I), or pharmacologically acceptable salts thereof, (I), where R¹ is hydrogen, halogen, nitro, amino, cyano, C_1-8 alkyl, C_1-8 alkoxy, C_1-8 alkyl, substituted with a halogen, C_1-8 alkoxy, substituted with a halogen, C_2-8 acyl or C_6-10 aryl; R² is hydrogen, C_1-8 alkyl, C_1-8 alkyl, substituted with a halogen, C_1-8 alkyl, substituted C_1-8 alkoxy, C_6-10-aryl or aralkyl, consisting of C_6-10 aryl and C_1-8 alkylene; each of R³, R⁴, R⁵ and R⁶ is independently hydrogen or C_1-8 alkyl; X is sulphur; Y is oxygen, NR⁸ or a bond, where R⁸ is hydrogen or C_1-8 alkyl; p equals 0 or 1; A is oxygen, CH₂ or N-OR⁹, where R⁹ is hydrogen, C_1-8 alkyl or aralkyl, consisting of C_1-8 aryl and C_1-8 alkylene; which are used as a PPAR activator.

EFFECT: improved method.

17 cl, 26 tbl, 31 ex