FIELD: molecular biology, biotechnology. SUBSTANCE: invention relates to preparing DNA fragment HC 250 that determines synthesis of polypeptide showing properties of human hepatitis C virus protein NS3. Polypeptide is prepared using the strain of bacterium Escherichia coli transformed with plasmid carrying DNA fragment HC 250. This polypeptide is able to bind antibodies to gene-encoding protein NS3 of hepatitis C virus. Invention is used in immunodiagnosis of human hepatitis C virus. EFFECT: improved method of preparing. 3 cl
| Title |
Year |
Author |
Number |
| DNA FRAGMENT HC 280 PREPARED BY CHEMICAL SYNTHESIS, RECOMBINANT POLYPEPTIDE HC 280 AT MOLECULAR MASS 120-130 KDA SHOWING CAPABILITY TO BIND ANTIBODIES TO GENE-ENCODING PROTEIN NS4 OF HEPATITIS C VIRUS PREPARED AT CULTIVATION OF THE STRAIN OF BACTERIUM ESCHERICHIA COLI - STRAIN OF BACTERIUM ESCHERICHIA COLI - A PRODUCER OF RECOMBINANT POLYPEPTIDE HC 280 SHOWING CAPABILITY TO BIND ANTIBODIES TO GENE-ENCODING PROTEIN NS4 OF HEPATITIS C VIRUS |
1993 |
- Loparev V.N.
- Krasnykh V.N.
- Blinov V.M.
- Gol'Tsov V.A.
- Zverev V.V.
- Sukhanova L.L.
- Alatortseva G.I.
|
RU2073718C1 |
| HC356 DEOXYRIBONUCLEIC ACID SEGMENT, POLYPEPTIDE, ESCHERICHIA COLI STRAIN AS PRODUCER OF POLYPEPTIDE CAPABLE OF BINDING HEPATITIS C VIRUS ANTIBODIES |
1993 |
- Krasnykh V.N.
- Loparev V.N.
- Blinov V.M.
- Gol'Tsov V.A.
- Zverev V.V.
- Sukhanova L.L.
- Alatortseva G.I.
|
RU2041949C1 |
| SET FOR ASSAY OF ANTIBODY TO THE HUMAN HEPATITIS C VIRUS (VARIANTS) |
1993 |
- Krasnykh V.N.
- Loparev V.N.
- Blinov V.M.
- Grinev A.A.
- Alatortseva G.I.
- Gol'Tsov V.A.
- Zajtsev I.Z.
- Sukhanova L.L.
- Zverev V.V.
- Poletaeva N.N.
|
RU2084527C1 |
| POLYPEPTIDE 1106 DESIGNATED FOR ASSAY OF ANTIBODIES TO HUMAN IMMUNODEFICIENCY VIRUS TYPE-1, FRAGMENT OF DNA H 1106 ENCODING POLYPEPTIDE 1106, RECOMBINANT PLASMID DNA PH 1106 ENCODING POLYPEPTIDE 1106, STRAIN OF BACTERIUM ESCHERICHIA COLI - A PRODUCER OF POLYPEPTIDE 1106 |
1992 |
- Sukhanova L.L.
- Alatortseva G.I.
- Gol'Tsov V.A.
- Alatortsev V.E.
- Zverev V.V.
- Poletaeva N.N.
- Blinov V.M.
- Grinev A.A.
- Krasnykh V.N.
|
RU2085586C1 |
| METHOD OF SYNTHESIS OF POLYPEPTIDE ELICITING ANTIGENIC ACTIVITY OF HEPATITIS E VIRUS AND SET FOR ASSAY OF ANTIBODY RAISED TO HEPATITIS E PATHOGEN |
1998 |
- Alatortseva G.I.
- Gol'Tsov V.A.
- Grinev A.A.
- Zverev V.V.
- Sukhanova L.L.
- Titaev A.V.
|
RU2172346C2 |
| POLYPEPTIDE DESIGNED FOR ANTIBODY ASSAY TO HUMAN IMMUNODEFICIENCY VIRUS OF THE SECOND TYPE, DNA FRAGMENT HE206 ENCODING POLYPEPTIDE E206, RECOMBINANT PLASMID DNA PHE206 ENCODING POLYPEPTIDE E206, STRAIN OF BACTERIUM ESCHERICHIA COLI - A PRODUCER OF POLYPEPTIDE E206 |
1992 |
- Zajtsev I.Z.
- Sukhanova L.L.
- Sazonov A.Eh.
- Karaseva E.V.
- Alatortseva G.I.
- Gol'Tsov V.A.
- Andzhaparidze O.G.
- Grinev A.A.
- Alatortsev V.E.
- Zverev V.V.
- Poletaeva N.N.
- Blinov V.M.
- Pokrovskij V.V.
- Suvorova Z.K.
- Buravtsova E.V.
- Krasnykh V.N.
- Jakovlev A.G.
- Amiantova I.I.
- Pugach A.V.
- Alekseev S.B.
- Chizhova M.M.
- Maljushova V.V.
|
RU2043412C1 |
| POLYPEPTIDE E117 DESIGNED FOR ANTIBODY ASSAY TO THE HUMAN IMMUNODEFICIENCY VIRUS OF THE FIRST TYPE, DNA FRAGMENT HE117 ENCODING POLYPEPTIDE E117, RECOMBINANT PLASMID DNA PHE117 ENCODING POLYPEPTIDE E117, STRAIN OF BACTERIUM ESCHERICHIA COLI - A PRODUCER OF POLYPEPTIDE E117 |
1992 |
- Zajtsev I.Z.
- Zvonarev A.Ju.
- Sukhanova L.L.
- Sazonov A.Eh.
- Karaseva E.V.
- Alatortseva G.I.
- Amiantova I.I.
- Gol'Tsov V.A.
- Andzhaparidze O.G.
- Alatortsev V.E.
- Zverev V.V.
- Poletaeva N.N.
- Blinov V.M.
- Titaev A.V.
|
RU2043413C1 |
| POLYPEPTIDE P102 DESIGNATED FOR ANTIBODY ASSAY TO HUMAN IMMUNODEFICIENCY VIRUS TYPE-1, DNA HP102-FRAGMENT ENCODING POLYPEPTIDE P102, RECOMBINANT PLASMID DNA PH A102 ENCODING POLYPEPTIDE P102, STRAIN OF BACTERIUM ESCHERICHIA COLI - A PRODUCER OF POLYPEPTIDE P102 |
1992 |
- Zajtsev I.Z.
- Sukhanova L.L.
- Alatortseva G.I.
- Gol'Tsov V.A.
- Grinev A.A.
- Alatortsev V.E.
- Zverev V.V.
- Poletaeva N.N.
- Blinov V.M.
- Noskova O.V.
- Lobanova A.L.
- Pokrovskij V.V.
- Suvorova Z.K.
- Buravtsova E.V.
- Krasnykh V.N.
|
RU2071502C1 |
| STRAIN OF ESCHERICHIA COLI BACTERIA - PRODUCER OF IL-29 RECOMBINANT PROTEIN |
2020 |
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- Lozhkov Aleksej Aleksandrovich
- Taraskin Aleksandr Sergeevich
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- Zabrodskaya Yana Aleksandrovna
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1992 |
- Zajtsev I.Z.
- Zvonarev A.Ju.
- Sukhanova L.L.
- Sazonov A.Eh.
- Karaseva E.V.
- Alatortseva G.I.
- Amiantova I.I.
- Gol'Tsov V.A.
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- Alatortsev V.E.
- Zverev V.V.
- Poletaeva N.N.
- Blinov V.M.
- Titaev A.V.
|
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