FIELD: medicine, molecular biology, genetic engineering of proteins. SUBSTANCE: invention proposes a method for preparing recombinant polypeptides for their using in set for assay of antibodies raised to hepatitis E virus. Set has series of recombinant antigens synthesized in E. coli cells transformed with recombinant DNAs. Recombinant DNAs involve fragment of the second and the third open reading frames of hepatitis E virus genome. Sets can contain E. coli β-galactosidase as a control antigen. EFFECT: enhanced sensitivity and specificity in assay of spectrum of antibodies to individual viral proteins. 6 cl, 2 tbl, 13 ex
| Title |
Year |
Author |
Number |
| HC356 DEOXYRIBONUCLEIC ACID SEGMENT, POLYPEPTIDE, ESCHERICHIA COLI STRAIN AS PRODUCER OF POLYPEPTIDE CAPABLE OF BINDING HEPATITIS C VIRUS ANTIBODIES |
1993 |
- Krasnykh V.N.
- Loparev V.N.
- Blinov V.M.
- Gol'Tsov V.A.
- Zverev V.V.
- Sukhanova L.L.
- Alatortseva G.I.
|
RU2041949C1 |
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1993 |
- Blinov V.M.
- Loparev V.N.
- Krasnykh V.N.
- Gol'Tsov V.A.
- Grinev A.A.
- Alatortseva G.I.
- Poletaeva N.N.
- Sukhanova L.L.
|
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1993 |
- Loparev V.N.
- Krasnykh V.N.
- Blinov V.M.
- Gol'Tsov V.A.
- Zverev V.V.
- Sukhanova L.L.
- Alatortseva G.I.
|
RU2073718C1 |
| POLYPEPTIDE 1106 DESIGNATED FOR ASSAY OF ANTIBODIES TO HUMAN IMMUNODEFICIENCY VIRUS TYPE-1, FRAGMENT OF DNA H 1106 ENCODING POLYPEPTIDE 1106, RECOMBINANT PLASMID DNA PH 1106 ENCODING POLYPEPTIDE 1106, STRAIN OF BACTERIUM ESCHERICHIA COLI - A PRODUCER OF POLYPEPTIDE 1106 |
1992 |
- Sukhanova L.L.
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- Gol'Tsov V.A.
- Alatortsev V.E.
- Zverev V.V.
- Poletaeva N.N.
- Blinov V.M.
- Grinev A.A.
- Krasnykh V.N.
|
RU2085586C1 |
| SET FOR ASSAY OF ANTIBODY TO THE HUMAN HEPATITIS C VIRUS (VARIANTS) |
1993 |
- Krasnykh V.N.
- Loparev V.N.
- Blinov V.M.
- Grinev A.A.
- Alatortseva G.I.
- Gol'Tsov V.A.
- Zajtsev I.Z.
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|
RU2084527C1 |
| POLYPEPTIDE P102 DESIGNATED FOR ANTIBODY ASSAY TO HUMAN IMMUNODEFICIENCY VIRUS TYPE-1, DNA HP102-FRAGMENT ENCODING POLYPEPTIDE P102, RECOMBINANT PLASMID DNA PH A102 ENCODING POLYPEPTIDE P102, STRAIN OF BACTERIUM ESCHERICHIA COLI - A PRODUCER OF POLYPEPTIDE P102 |
1992 |
- Zajtsev I.Z.
- Sukhanova L.L.
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- Gol'Tsov V.A.
- Grinev A.A.
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- Buravtsova E.V.
- Krasnykh V.N.
|
RU2071502C1 |
| POLYPEPTIDE DESIGNED FOR ANTIBODY ASSAY TO HUMAN IMMUNODEFICIENCY VIRUS OF THE SECOND TYPE, DNA FRAGMENT HE206 ENCODING POLYPEPTIDE E206, RECOMBINANT PLASMID DNA PHE206 ENCODING POLYPEPTIDE E206, STRAIN OF BACTERIUM ESCHERICHIA COLI - A PRODUCER OF POLYPEPTIDE E206 |
1992 |
- Zajtsev I.Z.
- Sukhanova L.L.
- Sazonov A.Eh.
- Karaseva E.V.
- Alatortseva G.I.
- Gol'Tsov V.A.
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- Alatortsev V.E.
- Zverev V.V.
- Poletaeva N.N.
- Blinov V.M.
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- Buravtsova E.V.
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- Jakovlev A.G.
- Amiantova I.I.
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- Alekseev S.B.
- Chizhova M.M.
- Maljushova V.V.
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1996 |
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