FIELD: pharmacy. SUBSTANCE: glycyrrham (glycyrrhizic acid monoammonium salt) is treated with 1.5% solution of H2SO4 at 98-102 C for 20-30 min and chloroform at room temperature. The formed technical glycoside is dissolved in acetone, glycoside tripotassium salt is precipitated by addition of spirituous (ethanol or methanol) solution of KOH (at pH = 8.5-9.0) and tripotassium salt is converted to monopotassium salt by recrystallization from glacial acid. Monopotassium salt is washed with glacial acid and converted to the end product by treatment with 1.5% solution of H2SO4 at 98-100 C at preliminary filtration at 55-60 C. Obtained glycoside is stirred with chloroform and dried. Yield is 50.0-58% (purity is 90-92%). Prepared product is used in medicine. EFFECT: improved method of preparing. 2 dwg
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