FIELD:organic chemistry, peptide synthesis. SUBSTANCE: synthesis is carried out by condensation of amino acid derivatives by method of series-parallel peptide chain splicing according the following scheme: 
. Method involves the use of arginine without protection of its guanidine group and synthesis of fragments 1-2 and 3-4 with nonprotected C-terminal carboxyl groups. Method ensures to carry out the preparative synthesis. Method can be used for synthesis of luliberine analogs in solution. EFFECT: higher efficiency. 2 cl
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