FIELD: organic chemistry, antibiotics. SUBSTANCE: product: (5R,6S)-2-carbam-oylhydroxymethyl-6-[(1R)-hydroxyethyl] -2-penem-3-carboxylic acid of the formula 
, empirical formula is C10H12O6N2S. Reagent 1: sodium (5R,6S)-2-carbamoylhydroxymethyl-6-[(1R)-hydroxyethyl]- -2-penem-3-carboxylate. Reagent 2: cation-exchange resin in H3-form or sulfuric, or hydrochloric acid. Reaction conditions: in medium of acetone, water or ethanol. Synthesized compound is used for pharmcomposition preparing. EFFECT: improved method of synthesis. 7 cl, 5 tbl
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|---|---|---|---|
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| METHOD OF OBTAINING DERIVATIVES OF PHENEM OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | 0 |
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SU1579461A3 |
| DERIVATIVES OF UREA, METHOD OF SYNTHESIS OF UREA DERIVATIVES, PHARMACEUTICAL COMPOSITION SHOWING INHIBITING ACTIVITY WITH RESPECT TO COA : CHOLESTEROL ACYLTRANSFERASE | 1992 |
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| METHOD OF PRODUCING OPTICALLY PURE (5R, 6S)-6-/1(R)-HYDROXYETHYL/-2-METHOXY-METHYLPENEM-3-CARBOLIC ACID OR ITS ESTERS OR SALTS WITH ALKALI METALS | 0 |
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| METHOD OF PRODUCING PENEM COMPOUNDS OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS OF ALKALI METALS | 0 |
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| OXOPROPANT-NITRILE DERIVATIVES OF CONDENSED PYRAZOLE OF PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSTIMULATING ACTIVITY, AND PHARMACEUTICAL COMPOSITION | 1990 |
|
RU2109735C1 |
