PENEM COMPOUNDS, THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION Russian patent published in 1997 - IPC

Abstract RU 2079498 C1

FIELD: organic chemistry and technology, antibiotics. SUBSTANCE: product: compound of the general formula (I) where R means the group a) -A-COOH where A means -(CH=CH)-, -OCH2- or -SCH2-, the group b) -(CH2)nSO2NHCN or heteroaryl and its pharmaceutically acceptable salts. Compounds were synthesized by interaction of compound (II) where R - as indicated above with compound of the general formula (III) where R' and R" - protective groups and Z - desplitting group. Compounds of the formula (I) show antibacterial activity and were used as active component of the pharmaceutical composition. EFFECT: improved method of synthesis. 5 cl, 2 tbl

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RU 2 079 498 C1

Authors

Dzhuzeppina Visentin[It]

Franko Zarini[It]

Daniehla Jabes[It]

Ehttore Perrone[It]

Kostantino Della Bruna[It]

Marko Alpegani[It]

Dates

1997-05-20Published

1992-06-22Filed