FIELD: organic chemistry. SUBSTANCE: compound of peneme having common formula 
where 
is group which protects hydroxyl is prepared by interaction of compound with common formula R′ where C1-C10 is mentioned above, Z is MS-CO-CH2-OCONH2-alkyl or optionally substituted phenyl, with compound having common formula III where M is atom of metal or cation of alkaline or alkaline-earth metal. The process is carried out at 20-100 C in the presence of anhydrous organic solvent within time from some minutes to some days. Then thus obtained compounds having common formula 
where R′ is mentioned above interacts with compound with common formula X-OC-COO-CH2-OOO-CH3 where X is atom of halogen. The process is followed by cyclization of product having common formula 
. EFFECT: improved efficiency. 21 cl
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