FIELD: medicine, pharmacy. SUBSTANCE: invention proposes the preparation that is complex of isonicotinic acid hydrazine with divalent iron of the formula: $$$. Preparation shows lower toxicity and increased activity as compared with isoniazide, prolonged action, does not form toxic metabolites in organism, exhibits the expressed bacteriostatic effect on mycobacterium strains that are resistant to streptomycin isoniazide. EFFECT: enhanced effectiveness of preparation. 10 tbl
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR LIMITATION OF COMPLICATIONS AND ADVERSE SYMPTOMS IN TREATMENT OF TUBERCULOSIS | 2001 |
|
RU2217137C2 |
ANTIALLERGIC AND ANTI-IFLAMMATORY AGENT | 1999 |
|
RU2170091C2 |
ANTIALLERGENIC AND ANTIINFLAMMATORY AGENT | 1999 |
|
RU2160097C1 |
MAGNESIUM 5-HYDROXYNICOTINATE SHOWING COMPLEX ANTIDIABETIC EFFECT | 1998 |
|
RU2136663C1 |
ISONICOTINOYLHYDRAZONES SHOWING ANTITUBERCULOSIS ACTIVITY | 1993 |
|
RU2054002C1 |
2-HYDROXY-3-METHOXYBENZALDEHYDE ISONICOTINOYL HYDRAZONE SHOWING ANTIASTHMATIC, ANTI-INFLAMMATORY AND ANTI-ALLERGIC ACTIVITY | 1997 |
|
RU2139711C1 |
ALKALINE SALTS OF AMIDES OF OROTIC ACID AND AMINO ACIDS, HAVING HYPERTENSIVE ACTION | 1995 |
|
RU2086543C1 |
MONO- OR DICARBOXYLIC ACID ZINC SALTS SHOWING GASTROPROTECING ACTIVITY | 1995 |
|
RU2116292C1 |
PHARMACEUTICAL COMPOSITION POSSESSING ANTIINFLAMMATORY, BRONCHOLYTIC, ANTI-TUBERCULOSIS ACTIVITY | 2011 |
|
RU2448961C1 |
DERIVATIVES OF 2-(3,4-DIHYDROXYPHENYL) ETHYLAMINE SHOWING IMMUNOTROPIC ACTIVITY AND CAPABILITY TO INHIBIT VIRUS REPLICATION | 1992 |
|
RU2039733C1 |
Authors
Dates
1997-05-27—Published
1994-06-21—Filed