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2 039 733

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C1

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Application

5057522/04, 1992-08-04

(22)

Actual filing date

1992-08-04

(45)

Published

1995-07-20

(72)

Inventor

Skachilova S.Ja.Azizov R.G.Zueva Eh.F.Burov Ju.V.Merkulova T.I.

(73)

Holder

Vserossijskij Nauchnyj Tsentr Po Bezopasnosti Biologicheski Aktivnykh Veshchestv

DERIVATIVES OF 2-(3,4-DIHYDROXYPHENYL) ETHYLAMINE SHOWING IMMUNOTROPIC ACTIVITY AND CAPABILITY TO INHIBIT VIRUS REPLICATION Russian patent published in 1995 - IPC

Abstract RU 2039733 C1

FIELD: organic chemistry. SUBSTANCE: product of the formula [2-R1O-3-R2O]Ph-(CH2)2-NHR2 where R1R2 a group -C(O)-Ph-NO2 -C(O)-CH(CH3)2 -C(O)-CH(C3H7)2 -C(O)-C6H11 -C(O)-CH2-C6H11 -C(O)-CH2-C5H9 -C(O)-CH2-Cl -C(O)-(CH2)3-Cl -C(O)-(CH2)4-Cl SO2C6H4CH3 -S(O)-O-Ph-Cl; -C(O)-Ad, where Ad 1-adamantyl, or R1 hydrogen and R2 as indicated above. Reagent 1: dopamine hydrochloride. Reagent 2: chloroanhydride of corresponding acid. Reaction condition: in pyridine medium, at 5-10 C. Derivatives were in substituted amine chemistry. EFFECT: improved method of synthesis. 3 cl, 6 tbl

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RU 2 039 733 C1

Authors

Skachilova S.Ja.

Azizov R.G.

Zueva Eh.F.

Burov Ju.V.

Merkulova T.I.

Dates

1995-07-20—Published

1992-08-04—Filed

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