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Application

98111395/04, 1998-06-10

(22)

Actual filing date

1998-06-10

(45)

Published

1999-09-10

(72)

Inventor

Smirnov L.D.Terekhina A.I.Kesarev O.G.Shaposhnikova G.I.Sernov L.N.

(73)

Holder

Vserossijskij Nauchnyj Tsentr Po Bezopasnosti Biologicheski Aktivnykh Veshchestv

MAGNESIUM 5-HYDROXYNICOTINATE SHOWING COMPLEX ANTIDIABETIC EFFECT Russian patent published in 1999 - IPC

Abstract RU 2136663 C1

FIELD: organic chemistry, medicine, endocrinology. SUBSTANCE: invention relates to a new compound - magnesium 5-hydroxynicotinate of the formula (I) , i. e. C12H16N2O10-Mg exhibiting a decomposition point above 300 C. In experiment on diabetic animals the compound (I) showed the complex antidiabetic effect resulting to the normalization of blood glucose and lipid level and processes of lipid peroxidation. The value LD50 for the compound (I) is 1600 mg/kg. The compound (I) is obtained by interaction of 5-hydroxynicotinic acid with magnesium oxide. EFFECT: enhanced antidiabetic effect of the compound. 5 tbl, 2 ex

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RU 2 136 663 C1

Authors

Smirnov L.D.

Terekhina A.I.

Kesarev O.G.

Shaposhnikova G.I.

Sernov L.N.

Dates

1999-09-10—Published

1998-06-10—Filed

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