FIELD: pharmacy. SUBSTANCE: agent has the pressed microcapsules containing NITROGLYCERIN. Microcapsules consist of microgranules containing, wt. -%: nitroglycerin, 7.7; barium sulfate, 13.1; egg powder, 5.6; vaselin oil, 5.2; ethylcellulose, 25.4; acetylnaphthylcellulose, 40.8; and lactose, 2.9. Microgranules were covered with polymeric shell containing lactose, methylcellulose and calcium stearate at the following ratio of components, wt. -%: nitroglycerin microgranules, 42-47; lactose, 47-51; methylcellulose, 1.5-2; and calcium stearate, the balance t up to 100. EFFECT: improved quality.
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Authors
Dates
1997-06-27—Published
1993-12-16—Filed