FIELD: medicine, pharmaceutical industry, pharmacy, biochemistry. SUBSTANCE: invention relates to a pentoxyphylline-base agent that is a purine derivative for oral using. Invention relates to a medicinal agent that is an antagonist of adenosine receptors and an inhibitor of phosphodiesterase. Agent comprises a core consisting of an active substance pentoxyphylline and starch, lactose, stearic acid and a surface modifying agent and an envelopment consisting of a cellulose derivative, titanium dioxide, a sliding substance taken in amount indicated in the invention claim. Invention provides the required quality, in part, satisfied strength, stability in storage, optimal rate of release being independently on activity of gastric and intestine juices and intestine peristalsis. EFFECT: improved and valuable properties of drug. 2 cl, 1 tbl, 1 ex
