FIELD: biology, peptides. SUBSTANCE: method involves brain tissue homogenization, acid extraction, precipitate separation and isolation of lyophilized preparation. Pineal gland tissue is extracted twice with 0.1-1.0 N perchloric acid aqueous solution at 2-6 C for 12-48 h. Extract is neutralized with potassium hydroxide aqueous solution followed by potassium perchlorate separation, purification and the preparation isolation by heating and double lyophilization of the neutralized extract. Preparation can be used in pharmacy, agriculture, medicine and veterinary science. EFFECT: improved method of preparing. 3 dwg, 1 tbl
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