DERIVATIVES OF ARYLSULFONEAMIDE OR THEIR SALTS AND PHARMACEUTICAL COMPOSITION SHOWING ANTIPROTECTIVE, ANTIHYPERTENSION AND VASOSPAMOLYTIC, IN PART, ANTIISCHEMIC ACTION Russian patent published in 1997 - IPC

FIELD: organic chemistry. SUBSTANCE: product: derivatives of arylsulfoneamide of the formula: where: R¹ - H, halogen; R² - H, halogen, CF₃; R³ - halogen, lower thioalkyl, trifluoromethoxy, lower alkyl, lower alkoxy, lower alkoxy-lower alkoxy, C₅-C₈-cycloalkyl, CF₃, phenyl-lower alkoxy, lower alkenyl, oxo-lower alkyl, hydroxyimini-lower alkyl, hydroxy-lower alkyl; or R² and R³ together form butadienyl; R⁵ - hydrogen, tetrahydropyrane-2; R⁶ - phenyl substituted with R⁷,R⁸ or benzyl substituted with R⁹,R¹⁰; R⁷ - hydrogen, lower alkyl; R⁸ - halogen, lower alkyl, lower alkoxy, lower thioalkyl, nitro-group; R⁹ - halogen, lower alkylhydroxy, lower thioalkyl, trifluoromethyl; R¹⁰ - hydrogen, lower thioalkyl, lower alkoxy; n = 2, 3, or their salts. Synthesized compounds were used as drugs. EFFECT: improved method of synthesis. 5 cl