DERIVATIVES OF N-ACYL-α-AMINO ACID OR THEIR PHYSIOLOGICALLY ACCEPTABLE SALTS, SIMPLE ETHERS OR ESTERS, AMIDES OR HYDRATES AND COMPOSITION INHIBITING ADHESIVE PROTEINS BINDING WITH PLATELETS AND PLATELET AGGREGATION Russian patent published in 1997 - IPC

FIELD: organic chemistry, amino acid derivatives. SUBSTANCE: invention proposes derivatives of N-acyl-α-amino acid or their physiologically acceptable salts, simple ethers or esters, amides or hydrates of the formula (I): α where: L - group of the formula R- or ; R - amidinine group; X - CH; Y - CH or N; H₂N(CH₂)_t - H, alk, alk-O-alk; R′ - H, alk. The synthesized compounds can be used for prophylaxis of diseases caused by binding adhesive proteins with platelets and platelet aggregation and acid-cellular adhesion also. Compounds of the formula (I) R″ were synthesized by splitting off protective groups at the corresponding positions and conversion of cyano-group to amidine group in the corresponding nitriles. EFFECT: improved method of synthesis. 15 cl, 5 tbl