FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to the novel sulfonamides of the general formula (I): 
where R1-R8, A and B have values given in the invention claim. Claimed compounds are inhibitors of endothelin and can be used for treatment of patients with diseases associated with endothelin activities, for example, hypertension and also to pharmaceutical compositions based on thereof. EFFECT: valuable curative properties of composition. 13 cl, 3 tbl, 77 ex
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