METHOD OF SYNTHESIS OF 6-METHYLURACIL-5-SULFOCHLORIDE Russian patent published in 1997 - IPC

Abstract RU 2087471 C1

FIELD: organic chemistry and technology. SUBSTANCE: method involves the successive interaction of 6-methyluracil with chlorosulfonic acid at 80-90 C and then with thionyl chloride at 60-75 C in the presence of catalytic amount of dimethylformamide (0.035-0.095 mole per 1 mole 6-methyluracil). Yield is 85-90%. Synthesized compound is used for synthesis of dyes and drugs. EFFECT: increased yield, decreased consumption of reagents and safety of sulfochlorination reaction. 1 tbl

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RU 2 087 471 C1

Authors

Makarov V.V.

Shirokogorova E.A.

Drobysheva N.E.

Firkin A.I.

Abdrakhmanov I.Sh.

Dates

1997-08-20—Published

1993-03-17—Filed