FIELD: medicine. SUBSTANCE: method involves producing opaque means having nonionogenic opaque means and nonionogenic iodinated opaque means by introducing sodium ions in the amount of 20-60 mmole/l. Sodium citrate being applied, sodium ions are introduced in the amount of 26-36 mmole/l. Ioverzol being applied as opaque substance, sodium ions are introduced in the amount required to reach the ion concentration of 26-36 mmole/l. The given means has iodinated radiopaque substance with contrast coefficient being equal to 3 or 6 and iodine concentration being equal to 100 mg/ml. Beside that, the substance has osmotic capacity less than 1 osm/kg of water and physiologically acceptable cations. The means provides enhanced contrast range. EFFECT: enhanced effectiveness of X-ray, magnetic resonance or ultrasonic examination. 10 cl, 3 dwg, 3 tbl
