METHOD OF PREPARING IONEXOL Russian patent published in 2001 - IPC

Abstract RU 2173315 C2

FIELD: chemical industry. SUBSTANCE: described is method of purifying raw iohexol by isolation of iohexol in the form of solid substance from first solvent and washing of solid iohexol with additional solvent to prepare iohexol of higher purity. Said first solvent comprises isopropanol and 2-methoxyethanol in volume ratio from 93:7 to 85:15 and said additional solvent comprises isopropanol. EFFECT: simplified process. 9 cl, 1 tbl _

Similar patents RU2173315C2

Title	Year	Author	Number
IODIXANOL SYNTHESIS	2005	Tservenka Jan Khussajn Khalid	RU2385316C2
PURIFICATION OF X-RAY CONTRAST AGENTS	2013	Cervenka Jan Thaning Mikkel Olsson Andreas Glogard Christian	RU2662941C2
CONTRAST AGENTS	2008	Taning Mikkel'	RU2469021C2
BIODEGRADABLE NONCOUPLED POLYMERS	1993	Jo Klaveness Kejt Redford Jan Solberg Per Strande	RU2114865C1
CONTRAST AGENTS AND THEIR USING	1993	Jo Klaveness Kejt Redford Pol Rungved Jan Solberg Per Strande Unni Nordbi Viggen	RU2122432C1
METHOD FOR OBTAINING YOMEPROL,THE CONTRAST AGENT	2019	Oh, Young-Seon Kim, Jung-Jin Lee, Young-Keun Cha, Young-Nam Oh, Gi-Bum	RU2795091C2
IODINATED ARYL COMPOUNDS AND DIAGNOSTIC COMPOSITION BASED THEREON	1995	Torsten Al'Men Sven Andersson Lars-Geran Vistrand Klaehs Gol'Man Ehjuvinn Antonsen Rune Fossejm Unni Nordbi Viggen Khokan Vikstrem Tomas Klingstedt Ib Leunbak Arne Berg Kharal'D Dugstad	RU2145955C1
METHOD OF OBTAINING THE PHARMACEUTICAL SUBSTANCE BASED ON IOHEXOLE	2017	Aleksandrov Aleksej Georgievich Arakelov Sergej Aleksandrovich Dozora Aleksej Evgenevich	RU2655619C1
IODINATED ESTERS	1990	Jo Klaveness[No] Per Strande[No]	RU2088579C1
PREPARATION OF INTERMEDIATES OF X-RAY CONTRAST AGENTS	2013	Haaland Torfinn	RU2659214C2

RU 2 173 315 C2

Authors

Mal'Te-Serenssen Dik

Ingvollstad Odd Ehjnar

Mjurbroten Ehspen

Dates

2001-09-10—Published

1997-08-29—Filed