FIELD: medicine, biochemistry. SUBSTANCE: invention relates to the use of oxidized glutathione as stimulating agent of endogenous production of cytokins and hemopoietic factors. The proposed agent is injection solution at concentration 0.01-2.0% in pharmaceutically acceptable solvent in the presence of hydrogen peroxide at concentration 0.003%. Agent is administrated by parenteral route at doses 0.01-0.5 mg/kg body mass (one or more injections per a day for one or more days or continuously up to curative effect). EFFECT: enhanced effectiveness of agent. 7 cl, 21 tbl, 4 dwg
| Title |
Year |
Author |
Number |
| AGENT FOR REGULATION OF ENDOGENOUS PRODUCTION OF CYTOKINE AND HEMOPOIETIC FACTOR (VARIANTS) AND METHOD OF ITS USING |
1996 |
- Balazovskij M.B.
- Kozhemjakin L.A.
|
RU2153351C2 |
| METHOD OF PREPARING OF OXIDIZED GLUTATHIONE-CIS- DIAMINODICHLOROPLATINUM COMPLEX AND PHARMACEUTICAL COMPOSITIONS BASED ON THIS COMPLEX FOR CONTROLLING METABOLISM, PROLIFERATION, AND DIFFERENTIATION, AND MECHANISMS OF APOPTOSIS OF NORMAL AND TRANSFORMATED CELLS |
1998 |
- Balazovskij M.B.
- Kozhemjakin L.A.
|
RU2144374C1 |
| HEXAPEPTIDE COMPOSITE WITH STABILIZED DISULFIDE BOND WITH SUBSTANCE-METAL, PHARMACEUTICAL COMPOSITIONS BASED ON SAID, METHODS OF THEIR PREPARING AND USE FOR TREATMENT OF DISEASES BASED ON REGULATION OF METABOLISM, PROLIFERATION, DIFFERENTIATION AND APOPTOSIS MECHANISMS IN NORMAL AND PATHOLOGICAL TISSUES |
1999 |
- Kozhemjakin L.A.
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|
RU2153350C1 |
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2011 |
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|
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| PHARMACEUTICAL COMPOSITION COMPRISING GLUTATHIONE DISULPHIDE AND GLUTATHIONE DISULFIDE S-OXIDE |
2017 |
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- Ignatenko Oleg Aleksandrovich
|
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2001 |
- Kozhemjakin L.A.
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|
RU2178710C1 |
| METHOD FOR STIMULATING ENDOGENOUS PRODUCTION OF CYTOKINES AND HEMOPOIETINS |
2012 |
- Gvozdeva Tat'Jana Sergeevna
- Dolgova Evgenija Vladimirovna
- Aljamkina Ekaterina Anatol'Evna
- Orishchenko Konstantin Evgen'Evich
- Proskurina Anastasija Sergeevna
- Rogachev Vladimir Alekseevich
- Nikolin Valerij Petrovich
- Popova Nelli Aleksandrovna
- Efremov Jaroslav Rejngol'Dovich
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|
RU2498821C1 |
| CYCLOPHERONE-BASED PHARMACEUTICAL COMPOSITION OF LOCAL OR EXTERNAL APPLICATION FOR TREATMENT OF PURULENT-DESTRUCTIVE AFFECTION OF MUCOUS MEMBRANE AND SKIN, GENERAL-SYSTEM DISEASES IN CASE OF IMMUNODEFICIENCY CONDITIONS (VERSIONS) |
2008 |
- Mezhburd Evgenij Vol'Fovich
- Kosjakova Ninel' Ivanovna
- Murashev Arkadij Nikolaevich
|
RU2414221C2 |
| TOPICAL AND EXTERNAL TILORONE PHARMACEUTICAL COMPOSITION FOR TREATMENT OF PURULENT-DESTRUCTIVE MUCOSAL AND SKIN DISEASES, SYSTEMIC DISEASES IN IMMUNODEFICIENCY STATES |
2008 |
- Mezhburd Evgenij Vol'Fovich
- Kosjakova Ninel' Ivanovna
- Murashev Arkadij Nikolaevich
|
RU2401104C2 |
| HEMOSTIMULANT AND PHARMACEUTICAL COMPOSITION AND METHOD FOR HEMOPOIESIS STIMULATION |
2011 |
- Balazovskij Mark Borisovich
- Antonov Viktor Georgievich
- Ignatenko Oleg Aleksandrovich
|
RU2482869C1 |
