FIELD: pharmaceutics.
SUBSTANCE: group of inventions relates to pharmaceutical industry, namely to pharmaceutical composition (and its use) for eliminating dose-related toxicity and increasing the therapeutic activity of a pharmacologically active compound in treatment of infectious and non-infectious diseases, glutathione disulphide or a pharmaceutically acceptable organic or inorganic salt thereof and a glutathione disulfide S-oxide or a pharmaceutically acceptable organic or inorganic salt thereof; as well as a pharmacological combination (and its use) comprising said composition and a pharmacologically active compound selected from an anticoagulant, a factor Xa inhibitor, an antimicrobial or antiviral agent, a calcium channel inhibitor; to a medicament comprising a therapeutically effective amount of said composition or combination together with pharmaceutically acceptable excipients.
EFFECT: group of inventions provides reduction of dose-dependent toxicity and the enhancement of the effectiveness of various pharmacotherapeutically active agents.
23 cl, 14 ex, 7 tbl, 6 dwg
| Title |
Year |
Author |
Number |
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|
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1998 |
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|
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|
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2001 |
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|
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2021 |
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2022 |
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|
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1999 |
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|
RU2153350C1 |
| STIMULATOR OF CYTOKIN AND HEMOPOIETIC FACTORS PRODUCTION AND A METHOD OF ITS USING |
1995 |
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|
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| INTERFERON CONJUGATES AND METHOD FOR PRODUCTION THEREOF |
2011 |
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2013 |
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