FIELD: medicine, pharmacy. SUBSTANCE: invention relates to biphase pharmaceutical composition that has MAO inhibitor and an inhibitor of absorption as an active agent in combination with usual pharmaceutically acceptable additions. In these compositions an active component, i. e. MAO inhibitor and an inhibitor of absorption is N-(1-phenylisopropyl)-N- -propinylamine or N-(4-fluorophenyl)-isoprop-1-yl-1-methyl- -propinylamine, or their salts, optically active isomers or metabolites. Invention relates to also methods of preparing a pharmaceutical composition showing optimal properties and prolonged release of an active component. EFFECT: improved method of preparing, enhanced effectiveness of composition. 17 cl, 8 tbl, 5 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| LIPOSOME COMPOSITION CONTAINING SELEGILIN, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION WITH MONOAMINOOXIDASE- INHIBITING ACTIVITY | 1995 |
|
RU2159106C2 |
| TRANSDERMAL ANHYDROUS COMPOSITION, METHOD OF ITS PREPARING AND APPLICATION | 1992 |
|
RU2088617C1 |
| PROCESS FOR PREPARING PHENYLKYLAMINES OR SALTS OF THESE COMPOUNDS | 1990 |
|
RU2015960C1 |
| METHOD OF SYNTHESIS OF PHENYLALKYLAMINES OF THEIRS PHARMACOLOGICALLY ACCEPTABLE SALTS | 1989 |
|
RU2007384C1 |
| DERIVATIVES OF 3,6-SUBSTITUTED-1,2,4,5-TETRAZINE, METHODS OF THEIR SYNTHESIS, LARVICIDE AND OVICIDE-ACTIVE COMPOSITION, METHOD OF ITS PREPARING AND METHOD OF DECREASE OF AMOUNT OF MITE LARVAE AND EGGS | 1994 |
|
RU2142949C1 |
| TLATRATE OF 7-ISOPROPOXYISOFLAVONE AND CYCLODEXTRINE POLYMER SHOWING ACTIVITY AGAINST OSTEOPOROSIS AND OSTEOMALACIA | 1987 |
|
RU2022970C1 |
| METHOD OF SYNTHESIS OF PROPARGYL AMMONIUM CHLORIDE DERIVATIVES | 1994 |
|
RU2130450C1 |
| ANTIMICROBIAL COMPOSITION | 1991 |
|
RU2030913C1 |
| METHOD OF SYNTHESIS OF QUINOLINECARBOXYLIC ACID DERIVATIVES | 1988 |
|
RU2014331C1 |
| METHOD OF SYNTHESIS OF QUINOLINE CARBOXYLIC ACID DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | 1988 |
|
RU2049783C1 |
