STRAIN OF THE HYBRID CULTURED ANIMAL CELL MUS MUSCULUS L - A PRODUCER OF MONOCLONAL ANTIBODY RAISED TO AUJESZKY'S DISEASE VIRUS, STRAIN UNIIEV-18B Russian patent published in 1997 - IPC

Abstract RU 2092554 C1

FIELD: veterinary biotechnology, virology. SUBSTANCE: invention relates to preparing the strain of the hybrid cultured cells Mus musculus L. producing antibodies raised to Aujeszky's disease virus, strain UNIIEV-18B. Strain is obtained by hybridization of murine myeloma cell (strain PAI) with splenocytes of murine strain Balb/c immunized with the strain UNIIEV-18B. Strain GVBAV-94/1 produces monoclonal antibodies of isotype IgG and their concentration in cultural and ascetic fluids - 10-20 mcg/ml and 20-30 mg/ml, respectively. Strain can be used for development of preparations used for diagnosis and prophylaxis of Aujeszky's disease. EFFECT: strain indicated above, enhanced effectiveness of antibodies. 1 tbl

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RU 2 092 554 C1

Authors

Globenko L.A.

Zhbanova T.V.

Kamalova N.E.

Mishchenko V.A.

Baborenko E.P.

Dates

1997-10-10Published

1995-04-19Filed