FIELD: veterinary biotechnology, virology. SUBSTANCE: invention relates to preparing the strain of the hybrid cultured cells Mus musculus L. producing antibodies raised to Aujeszky's disease virus, strain UNIIEV-18B. Strain is obtained by hybridization of murine myeloma cell (strain PAI) with splenocytes of murine strain Balb/c immunized with the strain UNIIEV-18B. Strain GVBAV-94/1 produces monoclonal antibodies of isotype IgG and their concentration in cultural and ascetic fluids - 10-20 mcg/ml and 20-30 mg/ml, respectively. Strain can be used for development of preparations used for diagnosis and prophylaxis of Aujeszky's disease. EFFECT: strain indicated above, enhanced effectiveness of antibodies. 1 tbl
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STRAIN OF HYBRID CULTURED CELLS OF ANIMAL MUS MUSCULUS L - A PRODUCER OF MONOCLONAL ANTIBODIES RAISED TO PIG VESICULAR DISEASE VIRUS, STRAIN T-75 | 1997 |
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Authors
Dates
1997-10-10—Published
1995-04-19—Filed