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2 093 144

(13)

C1

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IPC

(21) (22)

Application

92002744/14, 1992-10-28

(22)

Actual filing date

1992-10-28

(45)

Published

1997-10-20

(72)

Inventor

Korostin V.I.Belova V.V.Merkisheva Z.A.Fialkova M.A.Novokhatskij A.S.

(73)

Holder

Vsesojuznyj Nauchno-Issledovatel'Skij Institut Tekhnologii Krovezamenitelej I Gormonal'Nykh Preparatov

MEDICINAL PREPARATION FOR INJECTIONS Russian patent published in 1997 - IPC

Abstract RU 2093144 C1

FIELD: medicine, pharmacy. SUBSTANCE: invention proposes medicinal form of heparin for injection that contains 100-500 U/ml without toxic preserving agent and using in pediatry. Composition has,: heparin 0.075-0.56; sodium hydrogen phosphate 4.24-4.28; citric acid 0.24-0.26, and apyrogenic water - the rest, pH value of solution is 6.8-7.5. Sterility of solution is provided by sterilizing filtration in combination with the steam sterilization (at 110 C for 15 min). Preparation retains biological activity for 2 years. Preparation is used in pediatry as anticoagulating agent in ampoules (volume is 1 or 2 ml) containing 100 and 500 U/1 ml. EFFECT: enhanced effectiveness of preparation. 1 tbl

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RU 2 093 144 C1

Authors

Korostin V.I.

Belova V.V.

Merkisheva Z.A.

Fialkova M.A.

Novokhatskij A.S.

Dates

1997-10-20—Published

1992-10-28—Filed

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