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2 095 350

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Application

93047528/04, 1993-10-13

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Actual filing date

1993-10-13

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Published

1997-11-10

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Inventor

Glushkov R.G.Dronova L.N.Mashkovskij M.D.Gus'Kova T.A.Luk'Janova L.D.Romanova V.E.Chernobaeva G.N.Germanova Eh.L.

(73)

Holder

Tsentr Po Khimii Lekarstvennykh Sredstv

3-(N,N-DIMETHYLCARBAMOYLHYDROXY)-2-ETHYL-6-METHYLPYRIDINE SUCCINATE SHOWING ANTIHYPOXIC ACTIVITY Russian patent published in 1997 - IPC

Abstract RU 2095350 C1

FIELD: organic chemistry. SUBSTANCE: product: 3-(N,N-dimethylcarbamoylhydroxy)-2-ethyl-6-methylpyridine succinate of the formula (I) , empirical formula is C₂₆H₃₈N₄O₈, yield is 90%. Reagent 1: 2-ethyl-6-methyl-3-hydroxypyridine. Reagent 2: N,N-dimethyl-N-dichloromethylene ammonium chloride. Reagent 3: water. Reagent 4: alkali. Reagent 5: succinic acid. Reaction conditions: in medium of organic solvent, at boiling. The synthesized compound shows antihypoxic activity and used in medicine. EFFECT: improved method of synthesis. 5 tbl

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RU 2 095 350 C1

Authors

Glushkov R.G.

Dronova L.N.

Mashkovskij M.D.

Gus'Kova T.A.

Luk'Janova L.D.

Romanova V.E.

Chernobaeva G.N.

Germanova Eh.L.

Dates

1997-11-10—Published

1993-10-13—Filed