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2 099 323

(13)

C1

(51)

IPC

(21) (22)

Application

92016545/04, 1992-12-25

(22)

Actual filing date

1992-12-25

(45)

Published

1997-12-20

(72)

Inventor

Balasabraman'Jan Gopalan[In]

(73)

Holder

Dze Buts Kompani Pls

GUANIDINE DERIVATIVES, A METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION SHOWING HYPOGLYCEMIC ACTIVITY Russian patent published in 1997 - IPC

Abstract RU 2099323 C1

FIELD: organic chemistry. SUBSTANCE: invention proposes derivatives of guanidine of the formula (I): and their pharmaceutical acceptable salts where R1 means optionally substituted phenyl; R2 means optionally substituted amine; R3 - H or (C1-C4)-alkyl; R4 - H, (C1-C6)-alkyl, carbocyclic ring with 3-7 carbon atoms and others; R5 - H, halide, (C1-C4)-alkyl, (C1-C3)-alkoxy, S(O)mR8 and others. Invention proposes also a method of their synthesis and pharmaceutical composition showing HYPOGLYCEMIC activity. EFFECT: improved method of synthesis. 14 cl, 2 tbl

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RU 2 099 323 C1

Authors

Balasabraman'Jan Gopalan[In]

Dates

1997-12-20—Published

1992-12-25—Filed

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