SYNTHETIC OLIGOYPEPTIDES SPECIFICALLY INTERACTING WITH ANTIBODIES RAISED TO HEPATITIS C VIRUS, METHODS OF DIAGNOSIS HCV-INFECTION (VARIANTS) Russian patent published in 1998 - IPC

Abstract RU 2104284 C1

FIELD: medicine, molecular biology, virology. SUBSTANCE: invention proposes to use synthetic oligopeptides which are fragments of nonstructural protein NS4 of hepatitis C virus and corresponding amino acid residues 1711-1732 and 1921-1940. For diagnosis of HCV-infection using peptides exhibiting immunoreactivity with respect to antibody to hepatitis virus C antigenic mixture consists combination of indicated synthetic oligopeptides. For diagnosis using combination of proteins and peptides exhibiting immunoreactivity with respect to antibody to hepatitis C virus or based on recombinant nuclecapside hepatitis C virus protein (HCcAg) antigenic mixture has additionally indicated synthetic oligopeptides. EFFECT: simplified method of diagnosis. 5 cl, 3 tbl

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RU 2 104 284 C1

Authors

Firsova T.V.

Semiletov Ju.A.

Shibnev V.A.

Dates

1998-02-10Published

1994-10-20Filed