FIELD: medicine, molecular biology, virology. SUBSTANCE: invention proposes to use synthetic oligopeptides which are fragments of nonstructural protein NS4 of hepatitis C virus and corresponding amino acid residues 1711-1732 and 1921-1940. For diagnosis of HCV-infection using peptides exhibiting immunoreactivity with respect to antibody to hepatitis virus C antigenic mixture consists combination of indicated synthetic oligopeptides. For diagnosis using combination of proteins and peptides exhibiting immunoreactivity with respect to antibody to hepatitis C virus or based on recombinant nuclecapside hepatitis C virus protein (HCcAg) antigenic mixture has additionally indicated synthetic oligopeptides. EFFECT: simplified method of diagnosis. 5 cl, 3 tbl
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Authors
Dates
1998-02-10—Published
1994-10-20—Filed