FIELD: medicine, molecular immunology. SUBSTANCE: invention relates to the developed method for detection of antibodies to viral hepatitis C nuclear protein involving the contact of patient serum with antigen and conjugate. Synthetic peptide of the following structure is used as an antigen: NH2--Thr-Lys-Arg-Asn-Thr-Asn-Arg-Arg-Pro-Gln-Asp-Val-Lys-Phe- -Pro-Gly-Gly-Gly-Gln-Ile-Val-Gly-Gly-Val-Tyr-Leu-Leu-Pro-Arg- -Arg-Gly-Pro-Arg-Leu-Gly-CO-NH2. Monoclonal antibodies against human labeled with horse radish peroxidase are used as a conjugate. Invention provides diagnosis of hepatitis C at early stage. EFFECT: improved method of antibody detection. 8 tbl, 4 ex
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