TEST SYSTEM FOR DETECTING ANTIBODIES TO NUCLEAR PROTEIN OF HEPATITIS C OF IGM CLASS Russian patent published in 1999 - IPC

Abstract RU 2142134 C1

FIELD: medicine. SUBSTANCE: method involves applying synthetic peptide having structure NH2-Thr-Lys-Arg-Asn-Thr- Asn-Arg-Arg-Pro-Gln-Asp-Val-Lys-Phe-Pro-Gly-Gly-Gly-Gln-Ile-Val-Gly-Gly-Val-Tyr-Leu-Leu-Pro- Arg-Arg-Gly-Pro-Arg-Leu- Gly-CONH2, and monoclonal antibodies to human heavy IgM chains as conjugate base. Human sera inactivated by heating as negative and positive controls, phosphate salt solution with twin 80 detergent, solution for separating samples under study, citrate poising solution, orthophenyl diamine dihydrochloride, hydropyrite, sulfuric acid solution are included into the set. EFFECT: enhanced effectiveness in diagnosing acute hepatitis C. 10 tbl

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RU 2 142 134 C1

Authors

Mukomolov S.L.

Plotnikova V.A.

Zhebrun A.B.

Verbov V.N.

Kolobov A.A.

Kampe-Nemm E.A.

Shpen' V.M.

Dates

1999-11-27Published

1997-06-11Filed