METHOD OF PREPARING AN ANTIGEN FOR VACCINE SHOWING EFFECTIVENESS FOR PIG PROTECTION FROM INFECTION CAUSED BY MICROORGANISM OF GENUS MYCOPLASMA AND ACHOLEPLASMA OF ORDER MYCOPLASMATALES Russian patent published in 1998 - IPC

FIELD: veterinary science, vaccines. SUBSTANCE: invention relates to method of inactivation of organisms of genus Mycoplasma and Acholeplasma of order Mycoplasmatales. Method involves treatment of microorganisms with ethyleneimine or its suitable derivative. Microorganisms can be inactivated in situ by addition of 2-bromoethylamine hydrobromide to cultures up to weak alkaline medium reaction. Invention can be used for vaccine production against Mycoplasma hyopneumoniae in infected pigs. EFFECT: improved method of antigen preparing. 4 cl, 1 tbl